Mucormycosis caused by Saksenaea erythrospora is rarely reported in humans. Here are three previous reports in the literature, two associated with trauma and one as a cause of invasive rinosinustitis (India) all in immunocompetent patients. This is the first reported case of mucormycosis following esthetic surgery and was associated with a surgery medical tourism. Case presentation: we report a case study of S. erythrospora infection in an immunocompetent woman after the completion of esthetic surgery. Presenting as a rapidly progressive necrotizing infection of skin and soft tissue, which required bilateral mastectomy and extensive surgical debridement associated with prolonged antifungal therapy. The organism was identified phenotypically and confirmed biologically after rDNA amplification and sequencing. It is the first report from Colombia. Conclusions: Mucormycosis should be considered in the differential diagnosis of necrotizing infections of the skin and soft tissue that rapidly